Institute of Molecular Physiology is focused on studying molecular biology and molecular basis of physiological processes.
Molecular biology explores the nature of life based on its ever-expanding understanding to the genetic central dogma of biology and promotes technologies that can be widely applied in life sciences. Date back from the 1950s and 1970s respectively, the development of molecular biology and genetic engineering technology have largely propelled biomedical research and applications. Molecular physiology research includes studies on the basic molecular biology events such as gene duplication, repair, expression regulation, its regulation mechanism in important biological processes such as development, aging and disease, as well as research and application of molecular biology technologies in molecular evolution, gene editing, and molecular marker development.
Physiology started since Harvey's research in the circulation system in the 16th century, which is the foundation of modern medicine. The Institute of Molecular Physiology uses the concepts and technologies generated from molecular biology to promote physiology research, while the questions raised from physiology research stimulate the advancement and application of molecular biology technologies, including studies on the molecular mechanism and regulation of important physiological processes such as sleep, metabolism, immunity, perception and respiration, as well as the relationship between these process and disease.
Key Areas
Basic principles of molecular biology: DNA repair mechanisms, gene expression, transcriptional regulation, and the dynamics of these processes;
Molecular biology techniques: gene editing, molecular dynamic labeling, and gene therapy;
Important physiological processes: sleep perception circuits and its molecular mechanisms, metabolism, immune, respiration, and their interactions.